With billions of machines connected in the Industrial Internet of Things (IIoT) and quantum computing beginning to enable new possibilities at the Edge, the exploitation of AI to transform industrial products, manufacturing and systems is underway in earnest. GE Research sits at the nexus of the Cloud and the Edge, of hardware and software, to lead a new revolution of Industrial AI deployment that balances delivering better performance with maintaining safety and enables new capabilities while also strengthening security. Colin and Brent discuss new ways GE is driving more automated and intelligent capabilities to manage and improve GE's massive fleets of jet engines, power generation turbines and healthcare imaging.